NURS 3664 Lecture Notes - Lecture 7: Respiratory Center, Myasthenia Gravis, Pulmonary Compliance
Document Summary
Diaphragm contract (drops) more negative in lung vs. atmosphere. Accessory muscles: not used when we breathe typically diaphragm and negative pressure, when struggling to breathe, use accessory muscles. Anatomic dead space: some of each breath sits in anatomic dead space of nose, mouth, throat, with each breathe we take, we only get a % of air used and oxygen extracted. Co2 (70%)transported in plasma dissolved as hco3. Co2 (30%) transported bound to globin in rbc as carbaminohemoglobin. Co2 + h20 h2co3 hco3 - + h+ To maintain ph of 7. 4, 20 molecules of hco3 for 1 molecule of h+ Bod(cid:455)"s ph is 5(cid:1004)% (cid:272)o(cid:374)trolled (cid:271)(cid:455) co(cid:1006) Respiratory rate (rr) = 10 20 breaths per minute. Sigh breaths important in alveolar expansion, anatomical way of keeping alveoli open. Tidal volume (vt) = 400-800 ml depends on lung compliance: vt a = 250-650 ml, vt d = 150 ml anatomic dead space.
