NURS 3220 Lecture Notes - Lecture 27: Drug Tolerance, Hyperglycemia, Exocrine Gland
Document Summary
Sensed at dendrites, expressed at axon terminal: neurotransmission: incoming message, ap change to release transmitter, receptors on target cells, axons can be many feet long. Basic principles of neuropharmacology: manipulation of process of neurotransmission, neuropharmacologic agents, peripheral nervous system drugs, central nervous system drugs. Neuropharmacologic drugs can modify many diverse processes: skeletal muscle contraction, cardiac output, vascular tone, respiration, gastrointestinal function, uterine motility, glandular secretion, ideation, mood, and perception of pain. Neurons regulate physiologic processes: 3 mechanisms, sites of action: axons vs. synapse, steps in synaptic transmission, effects of drugs on the steps of synaptic transmission, how neurons regulate other cells. There are two basic steps in the process by which neurons elicit responses from other cells: (1) axonal conduction and (2) synaptic transmission. (t, neurotransmitter. ) Basic mechanisms of neuropharmacologic agents: sites of action: axons vs. synapses, axonal conduction, synaptic transmission, receptors.
