NURS 3220 Lecture Notes - Lecture 14: Diabetes Mellitus Type 1, Nph Insulin, Insulin Glulisine
Document Summary
Diabetes mellitus: overview of the disease and its treatment: disorder of carbohydrate metabolism, deficiency of insulin, resistance to action of insulin, sustained hyperglycemia, polyuria, polydipsia, ketonuria, and weight loss. Overview of diabetes treatment: primary goal is to prevent long-term complications, tight control of blood glucose level is important, controlling blood pressure and blood lipids also is important. Type i diabetes: requires a comprehensive plan. Isulin physiology: biosynthesis, secretion, metabolic actions, metabolic consequences of insulin deficiency, catabolic mode, increased glycogenolysis, increased gluconeogenesis, reduced glucose utilization. Types of insulin: short duration: rapid acting, insulin lispro [humalog, insulin aspart [novolog, insulin glulisine [apidra, short duration: slower acting, regular insulin [humulin r, novolin r] Intermediate duration: neutral protamine hagedorn (nph) insulin, insulin detemir [levemir, long duration, insulin glargine. Insulin lispro [humalog: analog of human insulin, rapid onset (10-20 minutes, short duration (3-5 hours, administered immediately before eating or even after eating.
