NURS 3110 Lecture Notes - Lecture 16: Sofosbuvir, Paritaprevir, Ritonavir
Document Summary
Amphotericin b = needs good kidney function. Anticipate infusion reaction = medicate with antipyretic, antihistamine, antinausea. Dna, no envelope, attachment fibers project from virus. Acute febrile pharyngitis: cough, fever, sore throat. Pharyngoconjunctivitis: cough, fever, sore throat, conjunctivitis (outbreaks at summer camps) Acute respiratory disease: pharyngitis, fever, cough (seen in young military recruits) Gi tract: infantile gastroenteritis (types 40 & 41) Culture: yes, except types 40/41 (electron microscopy or antigen detection) Rx: none available, vaccine for military recruits. A and b are seasonal, peak in winter) Antigenic shift - caused this to be more damaging to young people. Rna, envelope w/ hemagglutinin [h] & neurominidase [n] spikes. There are three types of influenza: a, b, and c. Shift = drastic antigenic changes new virus subtype (responsible for pandemics of influenza) Uncomplicated influenza: abrupt onset, fever, chills, headache, dry cough, muscle aches. Pneumonia: may result from influenza or secondary bacterial infections (s. aureus, h. influenza)
