NURS 3110 Lecture Notes - Lecture 6: Neonatal Conjunctivitis, Mucopurulent Discharge, Neisseria Gonorrhoeae
Document Summary
The cocci of medical importance, gram - cocci - neisseriacea. Require enriched medium ( chocolate agar) to see. Don"t survive well outside so typically get this through direct contact. Gram negative - outer membrane on outside and presence of lipopolysaccharides. Can live in oxidative environment or low oxygen environment. Evades host immune system by switching from one antigenic form to another. Gonococci attach mucous membranes of gi tract, eye, rectum, throat (because of fimbriae - which also slows phagocytosis) Males: develop urethritis with pus and painful urination, may expand to epididymitis, fibrous urethral strictures. Females: primary infection in endocervix, urethra, vagina with mucopurulent discharge. May progress to salpingitis (inflammation fallopian tubes) 20% infertility. All newborn infants get combined antibiotics and silver nitrate as a universal precaution of infection in eyes. Specimens: urethra, cervix, rectum, conjunctiva, throat, synovial. Looking for presence of gram negative diplococci tend to be in neutrophil.
