MCB 2410 Lecture Notes - Lecture 3: Chromosomal Inversion, Monosomy, Polyploid

21 views3 pages

Document Summary

One or more complete sets of chromosomes. Alters a characteristic due to unbalanced gene dosage. Paracentric inversion - does not include the centromere. Abcd*efg adcb*efg (paracentric inversion of bcd) Abcd*efg abe*dcfg (pericentric inversion of cd*e) May lead to alteration in gene function and regulation. Translocation - movement of genetic material between nonhomologous chromosomes. Loss of one member of the homologous pair. One additional member of an homologous pair. Nondisjunction - the failure of homologous chromosomes to properly segregate. Proper number and kind of chromosomes are required for proper development. Nondisjunction in meiosis i results in 4 abnormal gametes. Nondisjunction in meiosis ii results in 2 normal gametes and 2 abnormal gametes. Nondisjunction of sex chromosomes (x and y are pairing partners that normally segregate) Imbalance in sex chromosomes is less damaging than an imbalance in an autosome. Random x inactivation - only 1 x is in the active state while all others are inactive and condensed into barr bodies.

Get access

Grade+
$40 USD/m
Billed monthly
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
10 Verified Answers
Class+
$30 USD/m
Billed monthly
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
7 Verified Answers

Related Documents

Related Questions