MCB 2210 Lecture Notes - Lecture 23: Sox2, Chromatin, Oct-4
Document Summary
Somatic cell any cell that forms the body of a multicellular organism: any cell other than a gamete, germ cell, or stem cell. Some may lead to changes in gene expression that change the suite of proteins in the cell: transcription factors proteins that bind dna and can activate or repress the transcription of other genes. Sometimes these modifications can be stably inherited from one cell to another epigenetics. Stem cells undifferentiated cells that can reproduce themselves and also give rise to diverse specialized cell types: pluripotent stem cells can differentiate into any adult cell type. They cannot develop into an animal because they lack the potential to form a placenta: multipotent stem cells can give rise to cells from a limited number of lineages. Terminally differentiated cells cells that are considered to be permanently committed to a specific function.