MCB 2210 Lecture Notes - Lecture 26: Tumor Suppressor Gene, Cell Migration, Metastasis
17 Dec 2018
School
Department
Course
Professor
Document Summary
Sarcomas - cancer in connective or muscle tissues. Leukemias and lymphomas - cancer in blood cells. Cancer cells break the most basic rules of cell behavior that build and maintain organisms. Studying protein abnormalities, uncontrolled cell growth, increased cell division, decreased cell death, enhanced cell migration, etc teaches up about protein functions. Teach us about proteins involved in dna repair, cell signaling, cell cycle control, cell growth, programmed cell death, cytoskeletal rearrangement, and tissue architecture. Cancer cells: reproduce in defiance of the normal restraints on cell growth and division, invade and colonize territories normally reserved for other cells. Tumor (neoplasm) - new growth, occurs when a normal cell grows and proliferates out of control. Malignant - considered cancer if it invades other tissues. Metastasis - invasiveness or spread of cancer cells. Most cancers derive from a single abnormal cell with an heritable change.
