BIOL 1107 Lecture Notes - Lecture 3: Nitrogenous Base, Cytosine, Guanine

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10 Jul 2016
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Prions are proteins that genes in our body build. Job of prion: fold other proteins into their active states. Slide 33 shows 1 complete prion protein. Mutated prions fold normal proteins into abnormal forms that destroy brain cells. We can ingest mutated prions that are in other organisms" cns; they go into our. Cns and abnormally fold our proteins which then destroy our brain cells (this is referred to as mad cow disease) Proteins have 2 ends (c terminus and n terminus) The transition state is an unstable state in which the molecules have the potential to react with other stuff, to create new molecules. It requires energy to complete a reaction: activation energy. Typically we use heat as the activation energy. Need enough activation energy to get the chemical bonds to break apart to form new things. Delta g in the diagram is free energy that has now become available to the system from the reaction.

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