BIOL 3402 Lecture Notes - Lecture 5: Litre, Globin, Hemoglobin

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7 Nov 2016
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Carrying gas from alveoli to systemic tissues and vice versa. Oxygen transport: 98. 5% bound to hemoglobin, 1. 5% dissolved in plasma. Carbon dioxide transport: 90% hydrated to form carbonic acid, 5% bound to proteins, 5% dissolved in plasma. Exchange: 70% from carbonic acid, 23% from proteins, 7% from plasma. Oxygen: arterial blood carries about 20 ml of oxygen per deciliter, hemoglobin: for oxygen transport. Each with a heme group that binds one oxygen to an iron atom. 1 hemoglobin carry up to 4 oxygen. Deoxyhemoglobin hemoglobin with no oxygen: dissociation curve of hemoglobin. Carbon dioxide: carbon dioxide transported in 3 forms. Dissolved in plasma: 90% of carbon dioxide is hydrated to form carbonic acid. Then dissociates into bicarbonate and hydrogen ions: 5% binds to the amino groups of plasma proteins and hemoglobin to form carbamino compounds carbaminohemoglobin, does not compete with oxygen, hemoglobin can transport both simultaneously. Co competes for the oxygen binding sites on the hemoglobin molecules.

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