MIMG 102 Lecture Notes - Lecture 8: Lytic Cycle, Veterinary Virology, Syncytium

• School: UCLA
• Department: Microbiology, Immunology, and Molecular Genetics
• Course: MIMG 102
• Professor: Dasgupta Asim

Document Summary

Lec 8 intro animal viruses: viruses different from bacteria. E. g. types of enzyme; use viral enzyme translated from viral genome so can target the enzymes to develop anti-viral agents. Effect on host cell: lytic, fusion (syncytia formation), transformation (cancer) Something on cell surface attracts each other. E. g. hiv syncytia formation, infected cells form big cluster of cells. E. g. leukemia virus causes cancer (phage doesn"t!!: 4 types of infection with animal viruses. Latent infection, e. g. herpes; virus hibernates and comes back when immune system down. Viruses present but not harming the cell when in latent period. Replicate slowly & slow release of virus. Transformation of normal cells to tumor cells -> cancer: structure. Linear genome; no circular dna in animal viruses. Rna or dna virus (+ or - sense) Ss or ds some have nucleocapsid, others have membrane envelope, e. g. flu, herpes. To remove envelope, treat with soap; then there"s no viral protein recognizing cell receptors -> non-infectious infection events.