LIFESCI 3 Lecture Notes - Lecture 1: Walther Flemming, Gregor Mendel, Francis Crick
Document Summary
New material that we are responsible for: 3 class experiments demonstrate that dna is genetical material & proteins are not, frederick griffith, avery, macleod, & mccarty, a. hershey & m. chase, 1. ) Immune system can identify it bc it doesn"t have the capsule: 2. ) Avery experiment = extension of griffith"s experiment: "transforming principle" = molecule of heredity. Possible to label proteins & nucleic acids via use of radioactive isotopes of p & s. 32p --> important for labeling nucleic acids (know) bc dna has phosphorus but proteins do not. 35s --> important for labeling proteins (know) bc proteins have sulfur but dna does not: radioisotopes: diff forms of same element with diff number of neutrons & atomic mass. Atomic nuclei spontaneously decompose to form nuclei with higher stability: energy released during decomposition = radiation, experiment, 1. ) Phage containing p-labeled dna infected non radioactive cell: 2. )
