LIFESCI 2 Lecture Notes - Lecture 22: Nephron, Titin, Myofibril
Document Summary
Sensory neurons: allow for realization that stove is hot, motor neuron is then stimulated. Dark spots = myosin cross bridge binding sites: regulatory proteins sit on actin, cover binding sites on actin when in relaxed phase, tropomyosin ribbon protein. Binds myosin binding site on actin: troponin 3 spherical subunits. T-tubules ^ sarcoplasmic reticulum: special voltage sensitive calcium channels, dhpr (dihydropyridine receptors) found on t-tubules. Open do not permeate a lot of calcium, sends voltage: ruanodine receptors (foot proteins) found on lateral sacs of. Neuromuscular junction: brain spinal cord muscle, ach released ligand gated channels on muscle cell, when binded, sodium enters, leads to depolarization, epp = end plate potential. Small depolarization, same as graded potential: propagates along muscle cell. Neuro mishaps muscle activity = activation + inhibition botox: toxin produced by bacteria: clostridium botulinum inhibits neurotransmitter release, prevent wrinkles, wrinkles = overactive neurons.