LIFESCI 15 Lecture Notes - Lecture 17: Sertraline, Reuptake, Paroxetine

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18 Dec 2017
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Nervous system functioning: signal - initiates action potential in response to external stimuli: a sound, smell, sight, etc, travels from dendrite down axon, synapses with another cell - a muscle, gland or another neuron; causing a response/reaction. Action potential arrives at terminal button: 2. Calcium channels open and calcium rushes in: 3. Vesicles fuse with terminal button membrane: 4. Neurotransmitters = millions of small chemicals inside a vesicle that get dumped out into synapse. Acetylcholine released everywhere there is a motor neuron attached to a muscle: 5. Depends on intensity of signal: 6. ** at the synapse, an action potential is converted to a chemical signal, releasing nt to stimulate tissue or another neuron. There are pleasure centers in animal brains: 1954: james olds put electrodes in the mesolimbic area of rats" brains. Rats loved the sensation and would do anything to get it.

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