GE CLST 73B Lecture Notes - Lecture 4: Temporal Lobe, Aplysia, Episodic Memory

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In animals, one can train different memories at different times before a lesion to study consolidation. In humans, rely on memory for past events (famous events, famous people, one season. Tv shows- but all of these test for semantic memory) Give them a cue, and then you ask for an episodic memory. If they say my mom made me apple pies in fall then that"s semantic. Give me a memory that happens to deal with apple. But an episodic would be one fall picnic she made five apple pies picnic and she laid them on the porch and i fell on two of the pies. Amnesic patients give old memories but non-amnesic patients give very recent memories. Cellular: plastic change require gene transcription and translation- as thes take time (hours) System level: remote memories are insensitive to hippocampal (or medial temporal lobe) lesions- the neural representation of memory changes- this takes place over a long time frame (years)

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