GE CLST 73A Lecture Notes - Lecture 9: Second Messenger System, Motor Neuron, Microfibril

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Must have a voltage change to get synaptic transmission. Passive current flow = because of voltage. To depolarize the region in front of the active region that was going under the action potential. Due to the opening of a channel. Synaptic potential good for short distance communication. Action potentials are good for long distance communication. Every piece of membrane has voltage gated channels. What"s the consequence of making internodal region leaky. Action potential won"t reach the next node. Passive current is always large and will always depolarize the next. If too leaky, there won"t be enough to depolarize the next node. Exocytosis: neurotransmitters spit out to bind to the receptors. To prevent neurotransmitters from leaking, the synapse is very tight. When neurotransmitters get released, it binds to a receptor. Tremendous depolarization in the action potential due to depolarization. Increases conductions activates voltage gated calcium channel in the presynaptic terminal. Calcium is very important in neurotransmitter release.

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