GE CLST 70A Lecture Notes - Lecture 6: Genotype Frequency, Allele Frequency, Population Bottleneck

• School: UCLA
• Department: General Education Clusters
• Course: GE CLST 70A
• Professor: Friscia Anthony

Document Summary

So knowing that the incidence in the population is . 003, this is the same as knowing the probability that someone is genotype dd, i. e. , f(dd) = . 003. Imagine an infinitely large bucket full of gametes o. If i reach in and grab two alleles, what is the probability the genotype. If we let q = f(d) (the frequency of the d allele in the population) o. This is a diallelic locus (only 2 alleles at a locus) If we let p = f(d) p = 1-q = 1-. 055=. 945. Hardy-weinberg equilibrium: a statement of how allele frequencies relate to genotype frequencies under certain conditions. In a simple diallelic locus, like the one we"re talking about o o. Conditions for hardy-weinberg equilibrium o o o o o. If these aren"t met, then gene frequencies will change = evolution: humans usually mate assortatively: we find mates similar to ourselves random mating large populations no migration no mutation no natural selection o.