ZOO 3744 Lecture Notes - Lecture 2: Vagus Nerve, Axon Terminal, Skeletal Muscle
Document Summary
1897- physiologist chares sherrington gave the name synapses to the site of contact from one neuron to the other. Furshpan & potter were the ones to prove that electrical synapses existed. Otto lowei is the founder of chemical synapses. By studying the vagus nerve and the heart of frogs he discovered neurotransmitters (more specifically acetylcholine) Chemical synapses flow in one direction, from neuron to target cell. Axon terminal of a somatic neuron innervates a skeletal muscle fiber. Steps to an action potential in the muscle cell. Ca++ allows vesicles to move to the edge of the. Action potential travel down the axon of the presynaptic terminal and causes ca++ voltage-gated. Channels to open and ca++ flows into the cell. 4- the muscle cell generating an action potential (epsp) Ach binds to the ligand-gated na+ channels on. Peptides: dynorphin, enkephalins: released from secretory granules. Peptides synthesis in the soma and are transported to synapse.
