BME 50A Lecture Notes - Immunoglobulin G, Veterinary Virology, Basement Membrane
Document Summary
3 o transmembrane proteins differ from secretion because they get stuck into the membrane of the er by a start/stop hydrophic region of amino acids act as receptors etc. 4 o these guys can pass many more times then this with start/stop signals which are hydrophobic and want to be inside the membrane. 5 o the vesicle budding/fusion process: cop and clathrin are 2 coats use to bud: one between the er and golgi, the other between the golgi and cell membrane. 7: why it goes from er to golgi o, er, golgi disulfide bonds gylcosylation quality control. Modification of sugars aka can add mass sorting secretory pathways constitutive o o regulated happens all the time, no regulation. Will bud off the golgi like normal, but will be stopped before reaching the membrane. Will only go if the signal reaches it if no signal goes off, the secretory vesicles can store up and get rather big.