NPB 110 Lecture Notes - Lecture 11: Glucose Transporter, Active Transport, Epithelium

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Reabsorption of nat within pct on basolateral membrane of tubular epithelial cell , " nat hux into the cell and and cotransport other substances. Passive, secondary active transport using energy of nat gradient. Cotransport of substances such as glucose and amino acids into the cell. Cotransport of ht out of the cell (ht secretion ) Chloride ( cl -i reabsorbed due to attraction to nat ( electrical gradient ) , mostly para cellular. Water ( h2o) reabsorbed due to osmotic gradient created by movement of 10ns. " trans cellular with a qp - i aavaponn channel and paracellular. Potassium (kt) reabsorbed para cellularly through bulk how , cannot be reabsorbed trans cellviany against gradient. Imax : maximum rate that molecules can be absorbed due to limited transporters. Transport rate generally vanes with substance concentration in blood. " when glucose s 300mg 1ml then solt ( sodium - glucose) linked transporter completely reabsorbs glucose.

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