NPB 110 Lecture Notes - Lecture 5: Anethole, Vasopressin Receptor 2, Nephron
Document Summary
Each receptor specific for given hormone , but one hormone can act at different receptors. Can have different effects in different tissues na distinct receptors. Receptors expressed in target tissues and upon hormone binding inmate biochemical chain of events that alters cell function. Hydrophilic hormones : receptors in target cell membrane. " include gpcrs ( glucagon ) and tyrosine kinase receptors (insulin. Growth hormone , prolactin , leptin , immune system signaling molecules ( cytokines) have distinct class. " lipophilic hormones : intracellular receptors in nucleus. Same hormone can induce different effects in dlhereht cells t blood volume i t posterior pin11am. Activates 1173 , dao pathway to t catt and activate cam. Smooth muscle contraction to t blood pressure. Activates camp pathway to activate pka water channel mhmon in kidney tubules / t aavaponn gene transcription. One hormone can influence activity of another hormone at given target cell.