CHE 8A Lecture Notes - Lecture 18: Elimination Reaction, Nucleophile, Racemic Mixture
Document Summary
Reactions: comparing nucleophiles, the sn2 reaction, the sn1 reaction, the e2 reaction, the e1 reaction, comparing sn2/ sn1/e2/e1. Comparing nucleophiles nucleophile donates e to electropositive center. F solventscapable of it bonding can savate both. Nato stericeffects abulkier nucleophileis aworsenucleoph o betternu o. Fo lcio e br 0 10 a strongest nucleophile in polarproticsolvent polaraprotic solvent solvents that only exhibit dipole dipole interaction best non bonding. The sn2 reaction r k alkyinalide nucleophile methyl to z so naloalkane ratecmon na. Br rch i pen br pen a rcitz f. Ho by ho e g bimolecularnuclearsubstitution thetouowingwinneverbea leavinggroup. 30 20 to methyl stabiliarbocation casual s chf. The e2 reaction rate k alky halide nucleophile. H c c br i f i u. Zaitsev rule majorproduct in b elimination step has the more substituted double bond. The e1 reaction rate _k alkyl halide t hzot.
