BIS 2A Lecture Notes - Lecture 12: Nucleosome, Methyl Group, Repressor
Document Summary
Allosteric sites on transcription factors influence their ability to bind dna. Ex - transcription factor is inactive unless inducer is present. Ex - transcription factor is active unless inducer is present. If no lactose, repressor will stay bound because lactose metabolism is not needed. If lactose and glucose are present, neither repressor nor cap will bind because both metabolism needed. If glucose is high, cyclic-amp is low, and vice versa. A: not have transcription factors in the first place. A: they have different genes all together, and different gene regulation, and different expression of their genes. Differences in eukaryotes mrna made in nucleus in eukaryotes, not in the cytoplasm like for bacteria/archaea. Eukaryotes have the poly-a tail, introns, exons, bacteria/archaea don"t. Coils form around histones -> nucleosome; nucleosomes coil more to form supercoils; chromosomes are made from supercoils. Histone acetylation, add bulky acetyl group to nucleosome to spread histones out and make.