BIS 102 Lecture Notes - Lecture 11: Histidine, Hyperbola
Document Summary
" has 40 quaternary structure : tetramer composed of 4 subunits. " dark structure : same subunits have same to structure same. " hb composed of 751. a - helves. Protein folding for optimal binding of heme and reversible binding of 02. Red blood cells contain majority hb ( 300 106 hbl rbc) 1310concave structure increases surface area for diffusion of gases. In vivo function of hb lungs (ph 7. 6 )# tissues (ph 7. 2) Co2 (g ) coz (g) and ht oxy hb - 402 i waste from mitochondria no salt bridges (h - i. R (relaxed) state n 13 salt bridges hh deoxy hb " co2 - ht t ht co2 (9) t h2o. Co2 and ht changes in 40 structure between oxy hb and deoxy hb. " hb tetramer functions as 2 dimers deoxy hb oxy hb. " binding of o2 creates 8 weak bonds that balances the enemy of breaking 13 salt bridges.
