NUTR 200 Lecture Notes - Lecture 27: Iron Overload, Ferritin, Enterocyte
14 Jun 2020
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Document Summary
Iron released from proteins in foods: stomach acid, proteases. Iron absorbed in duodenum: first part small intestine, specific carrier proteins on enterocytes for different types of iron. Interacts with proteins on cells to deliver iron. Iron storage: ferritin, found in every cell, a lot in liver. Increasing and decreasing absorption: promote absorption, stomach acids and protease activity, vitamin c. Impair absorption: phytate (grains, beans, seeds), oxalate (leafy greens, supplemental calcium when consumed with an iron-containing meal. Factors to regulate total body iron: body supply is controlled by iron absorption. Iron status of the individual: type of iron in foods, amount of stomach acid for digestion, dietary factors, excretion, no excretory pathway, small daily iron doses, via cell sloughing, menstruation. Functions of iron: component of hemoglobin, carries oxygen in erythrocytes, component of myoglobin, carries oxygen in muscle cells, required for energy metabolism of carbohydrates, fats.
