PSB 3444 Lecture Notes - Lecture 15: Locus Coeruleus, Timothy Leary, Raphe Nuclei
Document Summary
Social and emotional changes from a drug. Any drug that has profound subjective and emotional effects. Meaningful images of people, characters, and animals. Similar chemical structures throughout lsd and ma like drugs. Derived from a fungus that can cause gangrene. Started a religion after his lsd trip. Lsd acts as a partial agonist 5hta. Cause suppression of output from locus coeruleus. Engage locus coeruleus, cortex, and raphe nuclei. Increases duration of excitatory action potentials mediated by serotonin in the cortex. Lsd is not taken continuously lik other drugs. People can be talk down if they are reminded that the drug is causing the effects. Too high of a dose with non experienced users. Mdma synthetic drug of mescaline and amphetamine. Was intended to be use as a therapeutic drug. Ended up being very powerful and use stop. Currently beings tested at low doses for treatment of ptsd. 8 hours to get rid from body completely.