BIOL 134 Lecture Notes - Lecture 6: Crystal Violet, Mycobacterium Tuberculosis, Atypical Pneumonia
Document Summary
A single thick layer of crosslinked peptidoglycan and teichoic acid molecules. Thick, rigid structure (paper maiche around a balloon) Porous, will allow many types of small molecules to pass through. O polysaccharide chain of sugars forms a coat around the outer membrane. Referred to as the o antigen , can make specific antibodies according to this chain of sugars. Lipid a when by itself in the membrane it is harmless endotoxin while the cell is intact, is no problem to us. If the cells dies and starts to be disassembled, it is released. Enough lipid a in our bloodstream can kill us. Surrounded by an outer membrane of phospholipids and lipopolysaccharides. Less penetrable by small molecules thanks to alternating hydrophobic and hydrophilic barriers. Crystal violet penetrates into the cell relatively easily. Iodine mortant causes crystal violet to crystalize, form large clumps.
