MAT 101 Lecture Notes - Lecture 9: Microsatellite, Allele Frequency, Partial Oxidation
8 Mar 2018
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How does forensic dna work: each person has 23 chromosomes. Each chromosome is a pair of dna strands. One half comes from your biological mother and the other from your biological father. Dna is built out of four bases: So dna are long strands of cs, gs, Short tandem repeats locations (str loci: before 2017, there were. 13 locations (loci) chosen on twelve chromosomes where short tandem repeating combinations of g, a, t, and c were found: for example, on vwa, which is on chromosome 12, the repeating sequence is. The number of times this sequence repeats on either half of chromosome. 12 is inherited from your biological parents: the number of repetitions is called an allele. Short tandem repeats locations (str loci: suppose at vwa you had alleles 13, 13 which is rare for a caucasian. The frequency of that pair is (0. 005)2 is. 0. 000025 or 0. 0025%, pretty rare: for an african-american however this particular pair occurs (0. 0157)2 is.
