BIOL 2443 Lecture Notes - Lecture 4: Connective Tissue, Amoeboid Movement, Chemotaxis
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50 70 percent: neutrophils, lymphocytes 20 40 percent, monocytes. < 1 percent: eosinophils, basophils, neutrophils, also called polymorphonuclear leukocytes (pmns, 50 70 percent of circulating wbcs, pale cytoplasmic granules containing, lysosomal enzymes, bactericidal (bacteria-killing) compounds. 19-4 fishbone diagrams for monitoring lab values: be familiar with these normal numbers, low rbc = anemia, high wbc = leukocytosis, low wbc = leukopenia, aplastic anemia all cells are low. Interleukin-6 (il-6: multi-csf, megakaryocytes, giant cells in red bone marrow, produce platelets by shedding membrane-enclosed packets of cytoplasm. Block 2: coagulation phase (blood clotting, begins 30 seconds or more after injury, depends on clotting factors (procoagulants, ca2+ and 11 different proteins, proenzymes (inactive enzymes, converted to active enzymes that direct reactions in clotting response. Many drugs that effect clotting factors try to alter the common pathway. Common clots = pulmonary embolism (clot in leg travels ad get stuck in lung bv); mi; stroke.
