PSY 302 Lecture Notes - Lecture 2: Decongestant, Peritoneum, Suppository
Document Summary
Study of effects of a drug on behavior. Study of the fate/movement of substances administered to the body. Entering body or a body compartment (ex: brain) Being carried to specific target organ (ex: blood) When want body to get used to the drug. Oral: easy, delayed (has to go through stomach/intestines and liver) Sublingual: easy (humans), bypass digestive system, (capillaries of the tongue) Intracerebral: bypass the blood brain barrier, local (specific brain area), mostly research. Intracerebroventricular: bypass the blood brain barrier, global effect, for emergencies. It is put under the tongue, goes directly into the blood through capillaries of the tongue. Fda considers 111 routes of administrations as valid. Study of the effect on some specific brain areas. Lipid-soluble (ex: heroine) substances pass the blood brain barrier. If the effect was proportional to the amount of drugs there would be a linear curve. Measures the dose of the drug and the effectiveness.