MIC 323 Lecture Notes - Lecture 8: Pelvic Inflammatory Disease, Neisseria, Diplococcus

• School: University of Miami
• Department: Microbiology and Immunology
• Course: MIC 323
• Professor: Schesser Kurt

Document Summary

6 - neisseria gonorrhoeae: gram diplococci. Infect cervix and urethra in woman and men, respectively: untreated leads to pid (pelvic inflammatory disease) 7: neisseria we know most about b/c we can do genetics stuff on it, o instead of p in lps vs los stands for oli instead of poly. 8 chlamydia: 1st obligate intracellular = like a virus in a way. Must infect cell to make more of itself since cannot replicate alone: differentiation involved, mostly asymptomatic. 17: had no genetic stuff but had whole genome sequenced = look for possible vfs, realized some of the orfs had proteins that could be substrates that could be secreted by a t3ss. 6 was turning pathway off in yersinia = nothing seen. 8 = take ca away and t3ss opens up and the band shows under conditions where t3ss are activated that some soluble copn is found: showing copn had potential to be a substrate for a chlamydia t3ss.