BIL 150 Lecture Notes - Lecture 12: Inositol, Cyclic Adenosine Monophosphate, Apoptosis
3 Oct 2016
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Document Summary
Receptors relay information to the cell and help it to adapt to a changing situation. Local signaling, may communicate by direct contact. Animal and plant cells have cell junctions to connect. Signaling substances in the cytosol can pass freely between adjacent cells. Long distance, releasing chemicals to tell the cell what to do. Releases the signal to target cells from secretory vesicles. Not physically in contact, but functionally in contact. Electrical signals are converted into chemical signals. A signalling molecule binds to a receptor protein, causing it to change shape. Both protein and molecule can change shape. Shape change is the initial transduction of the signal. Most signal receptors are plasma membrane proteins. Exterior binding site and interior binding site (that interacts with g. Gdp attaches to the receptor as it change shape. Binds to with rtks to form a dimer. Atp is required to make a fully activated rtk. Inactive relay proteins binds rtk to become active.
