BSCI 207 Lecture Notes - Lecture 30: G Protein–Coupled Receptor, Taste Receptor, Ion Channel
17 Nov 2016
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Document Summary
Why sense: find food, avoid predators, find mates, the brain provides integration of sensory input and guides response, sensory input integration motor output, brain determines behavioral response, animals rely on senses. Sensory receptor cells: subdermal sensory cells react to pressure, receive signal convert to neural output transduction cell output changes proportionately to input, sensory cells are neurons to they respond likewise. Ion channels vary across neuron: not all sensory neurons have action potentials. Ions lead stimulus results in proportional change in membrane potential- graded potential, stimulus proportional to neurotransmitter: receptor cells can respond with graded release of neurotransmitter. Sensory neurons couple receptor and ion channel. Ion channel is opened by a force: ex. Channel opened by a binding ligand- na of k or glutamate binds to taste receptor, channel opens: metabotropic- the stimulus binds to a receptor molecule, modified receptor activates g protein, ex. G protein coupled receptor- second messenger connects to ion channel.
