CH 461 Lecture Notes - Lecture 28: Cell Nucleus, Insulin Receptor, Blood Sugar

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12 Jul 2018
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They are one kind of mechanism for signaling among cells and tissues. Hormones can be defined as signaling molecules that one cell releases into the peripheral fluid or bloodstream, which alter the metabolism of the same or another cell. Hormones are distinguished from communication mechanisms that depend on direct cell cell contact through gap junctions. Hormones are also distinguished from neurotransmitters, although this distinction is somewhat artificial. Neurotransmitters can act as hormones and vice versa. Hormones act by binding to receptors, which are usually protein molecules. Receptors have two functions: first, they bind the hormone, and secondly, they transduce (change the type of) the signal to affect the metabolism of the recipient cell. The ability of a cell to respond to a hormone depends on two properties of the receptor molecule: how many of them are on a particular cell, and how well they bind the hormone.

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