CH 461 Lecture Notes - Lecture 3: Carnitine O-Palmitoyltransferase, Mitochondrion, Mitochondrial Matrix

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10 Jul 2018
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Activation: fatty acid fatty acyl coa of the fatty acid to a coa molecule in a two step process: The first step in utilizing the fatty acid molecule for energy production is the conversion energy source for the reaction. The inorganic pyrophosphate, pp i, is subsequently broken down to two phosphate ions by inorganic pyrophosphatase. The action of this enzyme means that very little pp i remains in the cell, making the synthesis of the fatty. Note that the hydrolysis of two high energy phosphate bonds in atp provides the acyl coa favored. This is an example of metabolic coupling, the process whereby a. A small molecule, carnitine, serves as a carrier across the mitochondrial membrane. This pathway requires no chemical energy supply; rather, the fact that the fatty acid in the mitochondrial matrix is being broken down by oxidation drives the process.

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