BSC 314 Lecture Notes - Lecture 34: Interphase, Prophase, Eukaryote

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27 Jun 2018
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Eukaryote Cell Divison: The Cell Cycle
When compared with prokaryotic cell division, the process isn't as simple in eukaryotes,
where linear chromosomes that are contained within a membrane bound nucleus have
to be apportioned equally between two daughter cells. If something goes wrong and
they aren't distributed equally, chances are the daughter cells will die for lack of
instructions on how properly to conduct the business of life. The eukaryote cell is also
filled with organelles and other cytoplasmic materials that must be divided. Small
wonder, then, that the process not only is more highly orchestrated, but that it takes
much longer to accomplish.
The essentially continuous process of cellular division in body ( somatic) cells has three
significant steps: 1.) the actual division of the nucleus, called mitosis;2.) the division of
the cytoplasmic material— cytokinesis—into two daughter cells after the nuclear
division; and 3.) the interphase just before and after division. The division to produce
sex cells ( gametes) is called meiosis and involves still other complications.
The entire sequence of repeating events from one mitotic division to the next is referred
to as the cell cycle. The cycle has two principal parts: 1.) interphase, divided
into G 1 (Gap 1), S (DNA synthesis), and G 2 (Gap 2) and, 2.) the M phase—the
combination of mitosis and cytokinesis. Figure diagrams the stages in the cycle, and
Table lists the events of significance in each. Figure diagrams the steps in mitosis.
The time to complete the cell cycle varies among species, the tissues in which the cells
occur, and general environmental conditions. Of the nuclear division stages, prophase
is the longest, and the separation and movement of the daughter chromatids in
anaphase is the shortest. Relative lengths might be: prophase 1 to 2+ hours,
metaphase 5 to 15 minutes, anaphase 2 to 10 minutes, and telophase 10 to 30 minutes.
A fourth interphase stage— G 0 —often is present in plants. It can occur at almost any
point and is induced by unfavorable growing conditions, such as the onset of cold winter
weather or by drought during the summer. It is a holding stage while the plant is
dormant.
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