BSC 469 Lecture Notes - Lecture 5: Coagulation, Alkaline Phosphatase, Chondrocyte

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To accommodate mechanical stress and the demands of calcium homeostasis, all bones are in a state of growth and resorption that occurs throughout life. Functions: rigid skeleton for support of body, attachment sites for muscles, protection for vital organs, hematopoiesis blood formation, reserves for calcium and phosphorus 99% of calcium is stored in bones. Consists of haversian canal, lamella, canaliculi, lacuna with osteocyte: haversian canal- central canal with blood vessels, nerves, lymphatics, lacunae with osteocyte- located within or between lamella. It consists of two layers: fibrous layer: consists mainly of collagenous fibers with small numbers of elastic fibers, osteogenic layer: vascular and cellular. The function is to attach the periosteum to the bone and to bind together the outer bone layers: all bone is supplied with blood vessels and nerves. The extracellular matrix of bone tissue consists of organic and inorganic components: organic material: type i collagen is the main fiber.

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