BSC 315 Lecture Notes - Lecture 7: Sister Chromatids, Ploidy, Centromere

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silvercicada472

28 Jan 2017

School

University of Alabama

Department

Biological Sciences

Course

BSC 315

Professor

Edwin Stephenson

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Document Summary

Post-mendel evidence that chromosomes contain genes: fertilization: sperm contains a nucleus and little else. Therefore, genes must be in nucleus: chromosomes: chromosome behavior parallels mendelian allele behavior, specific genes located on specific chromosomes (sex-linked inheritance in fruit flies) Diploid cell: 2 copies of each chromosome (except sex chromosomes). Diploid chromosome number = 2n: members of the pair are homologous chromosomes, or homologs. Haploid cell: 1 copy of each chromosome. Chromosomes are visible only during mitosis and meiosis, but not interphase. Germline = egg or sperm and precursor cells. Beginning of mitosis: each chromosome has 2 chromatids. End of mitosis: each chromosome has 1 chromatid. Sister chromatids: 2 parts of the same chromosome. Centromere position: metacentric - ~middle, acrocentric near one end. Chromosomes identified by: length, banding pattern with certain dyes, centromere position. Chromosomes and dna: each chromatid is a single dna molecule (average human chromosome: 10^8 base pairs and about 1000 genes)

Related Questions

M2A1 Worksheet: Mitosis and Meiosis

A dog is a diploid organisms and has 39 pairs of chromosomes (2n = 78), where n = 39 chromosomes from each parent. Use this example to answer the following question regarding chromosomal number.

INTERPHASE

How many chromosomes are present in the somatic cell?

What do they look like?

What are they âdoingâ in G1 of this phase?

What is happening in the S phase?

What is happening in the G2 phase?

What follows G2 phase in a somatic cell?

What follows G2 phase in a gamete cell?

MITOSIS

Number of chromosomes in the parent cell.

Number of chromatids in the parent cell.

Number of chromosomes in the daughter cell.

Number of chromatids in the daughter cell.

How many daughter cells are produced?

Are the daughter cells haploid or diploid?

How many cell divisions take place?

In what type of cell does this division occur?

Meiosis 1:

Number of chromosomes in the parent cell.

Number of chromatids in the parent cell.

Number of chromosomes in each Meiosis I daughter cell.

Number of chromatids in each Meiosis I daughter cell.

Are the daughter cells haploid or diploid at the end of Meiosis 1?

Meiosis II:

Number of chromosomes in the âparentâ cell (which is a daughter cell from Meiosis I).

Number of chromatids in the âparentâ cell.

Number of chromosomes in each Meiosis II daughter cell.

Number of chromatids in each Meiosis II daughter cell.

Are the daughter cells haploid or diploid at the end of Meiosis II?

Which phase or phases of Meiosis account for the genetic variability among the daughter cells? Howâ¦ what happens in this phase to create the diversity?

Comparing Mitosis and Meiosisâ¦..

How many daughter cells result from Mitosis? Are they diploid or haploid?

How many daughter cells result from Meiosis? Are they diploid or Haploid?

Cell structures and function: Match each organelle to its function:

Organelle Function

Lysosome 1. Lipid synthesis

Rough ER 2. Houses DNA

Nucleus 3. Energy extraction

Smooth ER 4. Dismantles debris

Golgi apparatus 5. detoxification

Mitochondria 6. Protein synthesis

Peroxisome 7. Processes secretions

What is the function of checkpoint proteins in the cell cycle?

How can all of a personâs cells contain exactly the same genetic material, yet specialize as bone cells, nerve cells, muscle cells and connective tissues?

What are the 3 primary germ layers?

Briefly, in one or two sentences, distinguish between

a bacterial cell and a eukaryotic cell

interphase and mitosis

mitosis and apoptosis

an autosome and a sex chromosome

homologous pair of chromosomes and a sister chromatid

centromere and centriole

chromosome and chromatid

monozygotic and dizygotic twins

allele and gene

13. Meiosis differs from mitosis in that:
a. meiosis results in the production of two new cells, whilemitosis results in the production for four new
cells., b. meiosis is used for growth and repair, while mitosis isused for production of eggs and sperm., c.
cytokinesis can be unequal following meiosis, but is approximatelyequal following mitosis., d. meiosis
involves one cell division, while mitosis involves two celldivisions., e. meiosis results in the production of
diploid cells, while mitosis results in the production of haploidcells.
14. Bits of maternal and paternal chromosomes are exchanged betweenhomologous chromosomes during
synapsis of meiosis I. This process is called:
a. crossing over., b. random mating., c. random fertilization., d.random shuffling of parental
chromosomes.,
e. mutation.
15. The advantage of sexual reproduction over asexual reproductionis that:
a. all young are genetically identical to the parent., b. malesmust evolve a copulatory organ., c. genetic
variability in the population is increased., d. females must evolvea vagina., e. mates are not needed.
16. Many different types of information are used to constructphylogenetic trees. Which of the following types
of information is the most direct measure of evolutionaryrelatedness?
a. physiology, b. gene sequence data, c. the fossil record, d.information about the structure of ribosomes.,
e. information about the structure of enzymes
17. A species is:
a. a group of individuals that can interbreed under naturalconditions and produce fertile offspring., b.
denoted by both a genus and a species name., c. the onlybiologically defined taxon., d. a group of
organisms with a large number of traits in common., e. all of theabove.
18. The process of spermatogenesis results in:
A. 4 diploid sperm; B. 1 diploid sperm and 3 haploid polar bodies;C. 1 haploid sperm and 3 haploid
polar bodies; D. 4 haploid sperm
19. Which cell division process results in an unequal division ofthe cytoplasm?
A. Spermatogenesis; B. Testiculargenesis; C. Oogenesis; D. None ofthe above
20. Meiosis is the process by which:
A. 1 diploid cell becomes 4 haploid cells; B. 1 diploid cellbecomes 1 haploid cell and 3 haploid polar
bodies; C. 1 haploid cell becomes 4 diploid cells; D. Both A andB
21. The phase of mitosis where chromosomes line up at the equator(middle) of the cell is called:
A. Anaphase; B. Telophase; C. Interphase; D. Metaphase
22. Chromosome #6 from Mom and Chromosome #6 from Dad form achromosome pair called:
A. Sister Chromatids; B. Centromeres; C. Homologous Chromosomes; D.Spindle Apparatus

scarlethare433

Ploidy refers to the number of complete sets of chromosomes (genes) present in a cell. The number of chromosomes in a complete set is a fixed characteristic of a species. Humans are diploid with two sets of 23 chromosomes. Fruit flies are diploid with two sets of 4 chromosomes. Sexually reproducing organisms are diploid, each somatic cell of an organism has two complete sets ("di" is a prefix indicating 2.). To complete a life cycle and reproduce new members of a species, mating is required. Mating brings a donation from a male and a donation from a female together. However, if the male and female cells remain diploid, the fertilization will result in a tetraploid zygote. In general, these are not viable. A mechanism is needed to form special haploid cells, gametes. The diploid set is split precisely into two complete haploid sets. That mechanism is meiosis.

The complete set of chromosomes of a species is also the complete set of genes of a species, the genome. (Yes, there is a minor contribution from mitochondria and chloroplasts. Inheritance of this information is "cytoplasmic".)

Please answer the following questions:

1. How many chromosomes in a brain cell of a fruit fly? How many chromosomes are in a liver cell of a human? Explain both answers.

2. How many chromosomes are in a fruit fly unfertilized egg? How many chromosomes are in a human egg? Explain both answers.

3. Why is meiosis necessary for sexually reproducing organisms? How many chromosomes are in a human zygote? Relate the two answers.

4. What is a gene allele? Suppose there is a gene called "bingo" and it is present once in a complete haploid set. How many alleles of "bingo" does a diploid individual have? How many copies or versions of the gene "bingo" are present in a diploid individual?

5. Modern DNA sequencing clearly identifies alleles by showing the different DNA sequence of each allele. These alleles may be termed structural alleles (I coined the term for this problem.). Classical genetics only dealt with phenotypes or visible traits. As a result, alleles of genes were identified by functionality, usually normal or non-functional. Using your knowledge of gene structure and gene expression, postulate a relationship between structural alleles and functional alleles. (include relative amounts; more, less, or equal).

BSC 315 Lecture Notes - Lecture 7: Sister Chromatids, Ploidy, Centromere

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