BSC 310 Lecture Notes - Lecture 23: Leucine Zipper, Catabolism, Riboswitch
3 Apr 2018
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Document Summary
Dna binding proteins: provide regulation in prokaryotes, short half-life of mrna allows for organism to respond quickly to environmental changes, regulation of transcription often requires proteins that can bind to. Enzyme is produced in response to a signal: usually affects catabolic (breakdown of larger molecules to smaller ones) processes, still a negative control due to repressor. Positive control of transcription: uses presence of an activator binding protein to enhance binding of. Rna polymerase to dna: create a change in dna structure, allowing rna polymerase to contact the promoter more readily. Can interact with rna polymerase directly: the location where the activator binds is called the activator- binding site and controls transcription of the operon. Big idea: many genes have promoters under positive control and promoters under negative control; many operons have promoters with multiple types of control and some have more than 1 promoter, each controlled independently.
