BSC 300 Lecture Notes - Lecture 2: Extremophile, Hematopoietic Stem Cell, Ribosomal Rna
Document Summary
Introduction to the study of cells and molecular biology. Outline the early history of cell biology. Describe the differences between prokaryotic and eukaryotic cells. Emphasize cell specialization as it relates to eukaryotic cells. Review the dimensions of size important to cell biology. Discuss how stem cells and ipscs may lead to breakthroughs in medical science. Cell biology is historically a reductionist science. By exploring similarities and difference of diverse cell types we can establish unifying themes of cellular processes. General principles applicable to human health, agriculture, biotechnology . Robert hooke first observed and named cells in 1655 using an elegant compound microscope with a magnification power of only about 50x. A simpler microscope using a single, small spherical lens. Increased magnification to almost 250x and eliminated aberrations and distortions. He described a miniature world of single cells organisms he called animalcules (protists) Van leeuwenhoek and his student, nicolaas hartsoeker, first to observe human spermatozoa.