BIOL 221 Lecture Notes - Lecture 6: Proximal Tubule, Paracellular Transport, Extracellular Fluid

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Summary of reabsorption in pct: about 65% of filtrate is reabsorbed, na+-k+-atpase (na+/k+ pumps) drive reabsorption of water and solutes, channels and transport molecules aid movement between filtrate and cytosol (facilitated diffusion, nearly all small organic nutrients. As stated before, about 65% of fluid that is filtered (becomes filtrate) is reabsorbed in the proximal convoluted tubule. The na+-k+-atpase (na+/k+ pumps) drives reabsorption of water and solutes by increasing the osmolality of the interstitial fluid. Channels and transport molecules aid movement of solutes between filtrate and cytosol (facilitated diffusion). Nearly all small organic nutrients are reabsorbed. Summary of reabsorption in pct: h+ move into filtrate by counter-transport (antiport; topic 11, some solutes move via paracellular route, water and solutes move into peritubular capillaries, osmolality of filtrate is about the same as plasma. In the proximal convoluted tubule hydrogen ions (h+) move into the filtrate by countertransport (antiport). Some solutes move via the paracellular route.

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