BIOL 221 Lecture Notes - Lecture 7: Fetal Hemoglobin, Hydroxycarbamide, Fetus

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Review your notes from the past few slides. Predict what values (high factor level of the factor or low level of the factor) favor oxygen unloading and which would favor loading. Recall that ph is a measure of the hydrogen ion concentration and is calculated as the negative log of that concentration; ph goes down as hydrogen ion concentration increases. Choose one to explain and share by posting on the discussion board. Mother"s blood at po2 = 35-50 mmhg. Fetus" blood at po2 = 30 mm hg is 80% saturated. 2 alpha & 2 gamma ( ) chains. Oxygen levels available to the fetus are much lower than those available to the mother and are dependent on the ability of the mother"s blood to carry oxygen. At the placenta the po2 of maternal blood is between 35-50 mm hg. Recall that hemoglobin is 75% saturated at 40 mm hg.

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