BIOL 221 Lecture Notes - Lecture 4: Hemorheology, Stroke Volume, Cardiac Output

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Slide 26 overview of factors contributing to blood pressure. In addition to cardiac output (covered with topic 2), peripheral resistance and blood volume play important roles in creating and maintaining blood pressure. Notice that blood volume doesn"t figure into any of equations needed to calculate cardiac output or mean arterial pressure. However, it does affect cardiac output by affecting end diastolic volume, which affects stroke volume (which is in the equation). Blood volume also directly affects the pressure in the vessels (similar to how air affects pressure in a balloon). The less blood you have, the lower the expected pressure. Dehydration is a decrease in water within the plasma that lowers blood volume; it is caused by excessive fluid loss through sweating, vomiting and diarrhea among other things. The more blood you have, the higher the expected pressure. Explain your answers and share them with the class by posting on the discussion board.

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