NSG 3315 Lecture Notes - Lecture 47: Collagen, Connective Tissue, Ground Substance

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22 Oct 2017
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Connective tissue: cells extracellular matrix ground substance intracellular protein bers collagen - strong insoluble; appear white (tendon, ligaments) elastin - allow stretch. Characteristics of tissue depend on the extracellular matrix. Ground substance is a gel containing 65%-80% water. Oxygen and food can diffuse through the gel. Therefore the tissue does not need blood vessels. Different types of cartilage are distinguished by how many protein bers are in the extracellular matrix; elastin found in matrix hyaline - pure; most abundant joins ribs to sternum and vertebra very few bers. Brocartilage - some elastin bers; intervertebral disks elastic - many bers; cartilage on ear. They block oxygen ad food diffusion, so bone must contain blood vessels. Osteocysts - live in the mature bone and maintain the extracellular matrix osteoclasts - break down the extracellular matrix bone chewing cells cause reabsorption of bone materials; release calcium and phosphate into bloodstream. Osteoblasts and osteoclasts are formed when they are needed to remodel bone.

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