PSY 3006 Lecture Notes - Lecture 8: Adaptive Immune System, Innate Immune System, Interleukin 6
Document Summary
T&b cells are part of the adaptive immune response that recognize non-self antigens. Macrophages secrete cytokines (chemical that gets released from a macrophage (and even the brain) Interleukin 6 is found more in people with depression. For decades, people thought the brain was immune privileged. Bbb- blood-brain barrier prevents most infections from reaching the brain. Changes in the support cells can really change brain function. The cells that are the brain"s innate immune response. But microglia are really flexible and can do different things in different situations. Stress and the brain and the immune system. Altered immune function and life stress in humans. Volunteers were exposed to a cold virus or saline. Those with more negative life events and poorer coping responses had higher rates of infection. Alzheimer"s caregivers (which is a stressful job) showed slower wound healing than age-matched controls. Hpa to gluccorticoids receptors to peripheral immune cells (so cort affects immune cells)