KINS 1224 Lecture Notes - Lecture 13: Mediastinum, Vocal Folds, Phonation

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Forms of immunity: cellular (cell-mediated) immunity, lymphocytes attack and destroy, pathogens inside cells, humoral (antibody-mediated) immunity, indirect attack of antibodies, pathogens inside body fluids. Antigens: molecule that triggers immune response, recognized as foreign by the immune system, antigen challenge, first encounter, generates antibodies in response, self-antigens vs non-self . Recognition: antigen presentation, t cell activation, attack, helper t cells, cytotoxic t cells, memory, recall response. Recognition: antigen presentation, migrates to lymph node and destroys t cells. T cell activation: costimulation, double check of apc, clonal selection. Attack: helper t cells, interleukins, attract neutrophils, nk cells, attract macrophages, stimulate t and b cells. Cytotoxic t cells: cytotoxic chemicals, lethal hit. Immune response: recruitment by helper t cells. Primary response: peaks in about a week, memory cells, during clonal selection, t cell recall response, quick attack when same pathogens appear, no noticeable illness. Recognition: antigen recognition, antigen presentation, clonal selection, differentiation, attack, neutralization, complement fixation, agglutination.

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