BIOL 1012 Lecture Notes - Lecture 28: Spindle Apparatus, Sister Chromatids, Cell Nucleus
Document Summary
The cell cycle includes growing and division phases. The cell cycle is an ordered sequence of events that extends from the time a cell is first formed from a dividing parent until its own division. Cell division is a continuum of dynamic changes: mitosis progresses through a series of stages, prophase, prometaphase, metaphase, anaphase, telophase. Cytokinesis often overlaps telophase: a mitotic spindle, is required to divide the chromosomes, guides the separation of the two sets of daughter chromosomes, is composed of microtubules and associated proteins. Spindle microtubules emerge from two centrosomes, microtubule-organizing regions in the cytoplasm of eukaryotic cells. Cell division is a continuum of dynamic changes. Interphase: the cytoplasmic contents double, two centrosomes form, chromosomes duplicate in the nucleus during the s phase. Prophase: in the nucleus, chromosomes become more tightly coiled and folded, in the cytoplasm, the mitotic spindle begins to form as microtubules rapidly grow out from the centrosomes.
