BIOL 1012 Lecture Notes - Lecture 12: Plant Cell, Integrin, Microtubule

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15 Feb 2017
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The (cid:272)ell"s i(cid:374)ter(cid:374)al skeleto(cid:374) helps orga(cid:374)ize its stru(cid:272)ture a(cid:374)d a(cid:272)ti(cid:448)ities: microtubules (made of tubulin) Act as tracks along which organelles equipped with motor proteins move: in animal cells, microtubules grow from centrosome, intermediate filaments. Reinforce cell shape and anchor some organelles. Often more permanent fixtures in cell: microfilaments. Attach to and exert sliding force on an adjacent doublet. The extracellular matrix of animal cells functions in support and regulation: synthesize an elaborate extracellular matrix (ecm) Protects and supports plasma membrane: ecm may attach to the cell through glycoproteins that bind to membrane proteins called integrins, integrins. Attach on the other side to proteins connected to microfilaments. Three types of cell junctions are found in animal tissues: adjacent cells adhere, interact and communicate through specialized junctions between them. Tight junctions prevent leakage of fluid across a layer of epithelial cells. Anchoring junctions fasten cells together into sheets. Gap junctions allow small molecules to flow through protein lined pores between cells.

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