BIOL 1001 Lecture Notes - Lecture 16: Dominance (Genetics), Probability Distribution, Twin Study

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Biol 1001 lecture 16 genetics and inheritance part ii. In a given population, the percentage of individuals in which a particular genotype is expressed. Inc. penetrance: polydactyly: penetrance percentage of people with a phenotype associated with a particular genotype, ex. Polydactyly: polydactyly is extra digits on feet or hands. Pleiotropy: pleiotropy single gene influences multiple phenotypic traits, alleles at single locus may have effects on two or more genetic traits, the ter(cid:373) pleiotropy (cid:272)o(cid:373)es fro(cid:373) the greek pleio (cid:373)ea(cid:374)i(cid:374)g (cid:862)(cid:373)a(cid:374)y(cid:863) a(cid:374)d tropo (cid:373)ea(cid:374)i(cid:374)g (cid:862)(cid:272)ha(cid:374)ges(cid:863) Ibib and ibi give type b blood ii (no alleles expressed) gives type o blood. Blood types in us: o-positive 38, o-negative 7, a-positive 34, a-negative 6, b-positive 9, b-negative 2, ab-positive 3, ab-negative 1% Genetic imprinting: the phenotype elicited from a locus is differentially modified by the sex of the parent contributing that particular allele. If heterozygous, and wild-type gene is not expressed will get the disorder.

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