NRSC 335 Lecture 15: Pain and Hearing

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Pain: unpleasant but adaptive, r are individuals that don"t perceive pain are scarred and deformed, and typically die young. P ain indicates that life may be in danger. P ain induced behavior, such as vocalization, may warn others about potential noxious stimuli. Fear, stress, and painful stimuli can induce analgesia: analgesia prevents recuperative behaviors (tending to. C hemical substances activate nerve terminals wounds: anatomy of p ain. C arry pain info to spinal cord: nociceptors - pain receptors, a fibers carry other cutaneous info (not pain) P ain info ascends to somatosensory cortex via spinothalamic tract. P eriaqueductal grey: g ets pain input, has important role in analgesia process. Inhibited by o piates: o piates suppress pain, o pium (from poppy, morphine, heroin, drugs bind to opiate receptors in brain. E ndorphins: brain has endogenous opiate transmitters, natural pain suppression, brain uses opiates to modulate pain transmission, descending modulation, o piate neurons in midbrain periaqueductal gray inhibit spinal pain signals.

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